Nanotechnology based assays for validating protein biomarkers

Posted by / 07-Jun-2020 23:32

Circulating exosomes have been studied as a promising biomarker for non-invasive cancer diagnosis, as they are implicated in tumor initiation, progression, and metastasis.

With ion Key/MS, new levels of sensitivity, reproducibility and robustness is achieved at flow-rates of 1 n L/min.Waters' solutions for biomarker verification and validation facilitate a smooth translation from discovery experiments to robust, high throughput, and high-sensitivity quantitative methods using tandem quadrupole or high-resolution time-of-flight MS systems.LC-MS based methods overcome many of the limitations of antibody-based techniques, such as ELISA or protein arrays, such as poor reproducibility, antibody development time, batch-to-batch reagent variability and the lack of multi-plexing capabilities.Detailed information on how Wiley uses cookies can be found in our Privacy Policy.Van Raemdonck GA, Osbak KK, Van Ostade X and Kenyon CR.

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If you would like to suggest an assay that is not currently available in our library as an idea for future development, please send an email to [email protected]